Three macrophage subsets are identified in the uterus during early human pregnancy

Unique Eomes+ NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy

Decidual and uterine natural killer (NK) cells have been shown to contribute to the successful pregnancy both in humans and mice. NK cells represent "cytotoxic" group 1 innate lymphoid cells (ILCs) and are distinct from the recently described "helper" ILC1. Here, we show that both in humans and mice the majority of group 1 ILC in endometrium/uterus and decidua express Eomesodermin (Eomes), thus...

Macrophage subsets in human atherosclerosis.

The position and spacing of implantation sites in the uterus of the rat during early pregnancy.

A study has been made of the distribution and spacing of implantation sites in the uterus of the rat at the 5th day of pregnancy. It has been shown that, whereas the implantation sites along the horns are distributed in an entirely random manner, the distances between the sites are significantly non-random. These results are similar to those previously described for the rabbit and the mouse, an...

Cyclin D3 in the mouse uterus is associated with the decidualization process during early pregnancy.

In the mouse, the attachment reaction between the blastocyst trophectoderm and the receptive uterine luminal epithelium occurs at 2200-2300 h on day 4 of pregnancy and is rapidly followed by transformation of stromal cells into decidual cells (decidual cell reaction). This process can also be induced experimentally (deciduoma) by intraluminal oil infusion in the uterus on day 4 of pseudopregnan...

Temporal and spatial expression of AIF in the mouse uterus during early pregnancy.

Apoptosis-inducing factor (AIF) is a phylogenetically old, bifunctional protein with a pro-apoptotic function and redox activity. AIF regulates apoptosis and also plays a role in the defense against stress depending on its subcellular localization. Embryo implantation is a complicated process, in which an activated blastocyst interacts with a receptive uterus. The expression and regulation of A...